FBXL4 antibody (N-Term)

Catalog No. ABIN2785924

This Rabbit Polyclonal antibody specifically detects FBXL4 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Horse, Pig and Rabbit.

Quick Overview for FBXL4 antibody (N-Term) (ABIN2785924)

Target: FBXL4 (F-Box and Leucine-Rich Repeat Protein 4 (FBXL4))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXL4 Antibody

Binding Specificity: N-Term

Sequence: VLETYHPGAV IRILACSANP YSPNPPAEVR WEILWSERPT KVNASQARQF

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXL4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXL4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXL4

Target: FBXL4 (F-Box and Leucine-Rich Repeat Protein 4 (FBXL4))

Alternative Name: FBXL4

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats.
Alias Symbols: FBL4, FBL5
Protein Interaction Partner: ERLEC1, CLGN, KDM4A, UBC, SKP1,
Protein Size: 621

Molecular Weight: 70 kDa

Gene ID: 26235

NCBI Accession: NM_012160, NP_036292

UniProt: Q9UKA2