NOMO1 antibody (N-Term)

Catalog No. ABIN2785996

This anti-NOMO1 antibody is a Rabbit Polyclonal antibody detecting NOMO1 in WB. Suitable for Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog and Zebrafish (Danio rerio).

Quick Overview for NOMO1 antibody (N-Term) (ABIN2785996)

Target: NOMO1 (NODAL Modulator 1 (NOMO1))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOMO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NOMO1 Antibody

Binding Specificity: N-Term

Sequence: DGSFRLENIT TGTYTIHAQK EHLYFETVTI KIAPNTPQLA DIIATGFSVC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against NOMO1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NOMO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1222 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NOMO1

Target: NOMO1 (NODAL Modulator 1 (NOMO1))

Alternative Name: NOMO1

Background: NOMO1 was originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE).
Alias Symbols: Nomo, PM5, NOMO3
Protein Interaction Partner: UBC, TRIM63, TRIM55, EXOSC10, FBXO6, UPF2, STAT1, ECT2, TIMM10, PLEC, ILF3, UBQLN4, SHBG, CDK2, TOM1L1, BAG6, NCLN,
Protein Size: 1222

Molecular Weight: 134 kDa

Gene ID: 23420

NCBI Accession: NM_014287, NP_055102

UniProt: P69849