EDC4 antibody (N-Term)

Catalog No. ABIN2786009

The Rabbit Polyclonal anti-EDC4 antibody has been validated for WB. It is suitable to detect EDC4 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for EDC4 antibody (N-Term) (ABIN2786009)

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EDC4 Antibody

Binding Specificity: N-Term

Sequence: LQEKQVICLS GDDSSTCIGI LAKEVEIVAS SDSSISSKAR GSNKVKIQPV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against EDC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1401 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-EDC4 antibody (ABIN2786009)

Wang, Xu, Li, Li: "Synthesis, characterization, and antitumoral activity of polyoxometalate loaded starch nanocomplexes." in: Journal of nanoscience and nanotechnology, Vol. 5, Issue 6, pp. 905-8, (2005) (PubMed).

Target Details for EDC4

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Alternative Name: EDC4

Background: In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro).
Alias Symbols: Ge-1, HEDLS, RCD-8
Protein Interaction Partner: MDM2, DCP1B, DCP1A, UBC, DCP2, LGR4, WWOX, RPA3, RPA2, RPA1, BMI1, DIMT1, NELFB, IGF2BP3, G3BP1, EIF2B2, EIF2B3, RFC4, NMT1, ILF2, FKBP3, DDX1, ABCF1, ZFP36, YTHDC1, EDC3, vpu, GIT2, FBLN1, CCL5, UPF1, CRK, SIRT7, EIF2AK2, Edc4, Pds5a, tat,
Protein Size: 1401

Molecular Weight: 152 kDa

Gene ID: 23644

NCBI Accession: NM_014329, NP_055144

UniProt: Q6P2E9