FAM120A antibody (Middle Region)

Catalog No. ABIN2786049

The Rabbit Polyclonal anti-FAM120A antibody has been validated for WB. It is suitable to detect FAM120A in samples from Human, Mouse, Rat, Rabbit, Cow, Dog, Horse and Pig.

Quick Overview for FAM120A antibody (Middle Region) (ABIN2786049)

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM120A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAM120A Antibody

Binding Specificity: Middle Region

Sequence: SGGATNHISG NKIGWEKTGS HSEPQARGDP GDQTKAEGSS TASSGSQLAE

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 92%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against FAM120A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM120A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1118 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FAM120A

Target: FAM120A (Family with Sequence Similarity 120A (FAM120A))

Alternative Name: FAM120A

Background: FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Alias Symbols: C9orf10, DNAPTP1, DNAPTP5, MGC111527, MGC133257, OSSA
Protein Interaction Partner: SPRTN, CEP250, SUMO2, STAU1, UBC, PASK, SUMO1, NEDD8, RNF2, EZH2, BMI1, HECW2, TARDBP, CFTR, GRK5, CAND1, CUL3, SIRT7, Ybx1,
Protein Size: 1118

Molecular Weight: 122 kDa

Gene ID: 23196

NCBI Accession: NM_014612, NP_055427

UniProt: Q9NZB2