CDK19 antibody (C-Term)

Catalog No. ABIN2786077

Product Details anti-CDK19 Antibody

Target: CDK19 (Cyclin-Dependent Kinase 19 (CDK19))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK19 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLTMDPTKRI TSEQALQDPY FQEDPLPTLD VFAGCQIPYP KREFLNEDDP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CDK19. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK19

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK19

Target: CDK19 (Cyclin-Dependent Kinase 19 (CDK19))

Alternative Name: CDK19 (CDK19 Products)

Background: This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
Protein Interaction Partner: MED6, MED13, MED12, MED24, MED20, MED7, MED22, MASP1, MED1, PIP, CLU, CCNC, AZGP1, APOD, MED17, MED23, MED14, MED11, MED8, MED30, MED28, MED29, MED9, MED18, MED15, MED31, MED4, MED13L, CDK19, ERC1, MED16, MED27, MED19, MED26, NIFK, RNPC3, COMMD4, CUTA, MY
Protein Size: 442

Molecular Weight: 48 kDa

Gene ID: 23097

Pathways: Regulation of Lipid Metabolism by PPARalpha