CDK19 antibody (C-Term)

Catalog No. ABIN2786077

The Rabbit Polyclonal anti-CDK19 antibody has been validated for WB. It is suitable to detect CDK19 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CDK19 antibody (C-Term) (ABIN2786077)

Target: CDK19 (Cyclin-Dependent Kinase 19 (CDK19))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK19 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK19 Antibody

Binding Specificity: C-Term

Sequence: LLTMDPTKRI TSEQALQDPY FQEDPLPTLD VFAGCQIPYP KREFLNEDDP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CDK19. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK19

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK19

Target: CDK19 (Cyclin-Dependent Kinase 19 (CDK19))

Alternative Name: CDK19

Background: This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
Protein Interaction Partner: MED6, MED13, MED12, MED24, MED20, MED7, MED22, MASP1, MED1, PIP, CLU, CCNC, AZGP1, APOD, MED17, MED23, MED14, MED11, MED8, MED30, MED28, MED29, MED9, MED18, MED15, MED31, MED4, MED13L, CDK19, ERC1, MED16, MED27, MED19, MED26, NIFK, RNPC3, COMMD4, CUTA, MY
Protein Size: 442

Molecular Weight: 48 kDa

Gene ID: 23097

Pathways: Regulation of Lipid Metabolism by PPARalpha