SAMHD1 antibody (Middle Region)

Catalog No. ABIN2786114

This Rabbit Polyclonal antibody specifically detects SAMHD1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for SAMHD1 antibody (Middle Region) (ABIN2786114)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SAMHD1 Antibody

Binding Specificity: Middle Region

Sequence: KGRPENKSFL YEIVSNKRNG IDVDKWDYFA RDCHHLGIQN NFDYKRFIKF

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against SAMHD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SAMHD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 626 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1

Background: SAMHD1 contains 1 HD domain and 1 SAM (sterile alpha motif) domain. SAMHD1 may play a role in mediating proinflammatory responses to TNF-alpha signaling.
Alias Symbols: AGS5, DCIP, HDDC1, MOP-5, SBBI88, CHBL2
Protein Interaction Partner: SUMO2, SKP2, CDK2, CDK1, CCNA2, HSF5, SUMO1, UBC, NEDD8, RNF2, TRMT1, GANAB, XPO7, FAF1, HSPH1, SEC23A, PRMT3, RANBP3, SF1, XRCC5, TUBG1, SUPT5H, RPL24, PLOD2, OSBP, NARS, JUP, MSH6, GART, XRCC6, EIF4B, ATP6V1E1, FBXO25, KPNB1, vpx, RBX1, CD81, BARD1, APP
Protein Size: 626

Molecular Weight: 72 kDa

Gene ID: 25939

NCBI Accession: NM_015474, NP_056289

UniProt: Q9Y3Z3