SH2B1 antibody (Middle Region)

Catalog No. ABIN2786119

The Rabbit Polyclonal anti-SH2B1 antibody has been validated for WB and IHC. It is suitable to detect SH2B1 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Cow.

Quick Overview for SH2B1 antibody (Middle Region) (ABIN2786119)

Target: SH2B1 (SH2B Adaptor Protein 1 (SH2B1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SH2B1 Antibody

Binding Specificity: Middle Region

Sequence: GTSFLTRENT DSLELSCLNH SESLPSQDLL LGPSESNDRL SQGAYGGLSD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SH2B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SH2B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 671 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH2B1

Target: SH2B1 (SH2B Adaptor Protein 1 (SH2B1))

Alternative Name: SH2B1

Background: SH2B1 is a member of the SH2-domain containing mediators family. SH2B1 mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation.
Alias Symbols: DKFZp547G1110, FLJ30542, SH2-B, SH2B, PSM
Protein Interaction Partner: FGFR3, SH2B1, SH2B2, JAK2, INSR, IGF1R, RHBG, EGFR, IRS1, BRCA1, KIAA0319, NTRK2, NTRK1, GRB2,
Protein Size: 671

Molecular Weight: 71 kDa

Gene ID: 25970

NCBI Accession: NM_015503, NP_056318