Amphiphysin antibody (N-Term)

Catalog No. ABIN2786208

The Rabbit Polyclonal anti-Amphiphysin antibody has been validated for WB. It is suitable to detect Amphiphysin in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig and Zebrafish (Danio rerio).

Quick Overview for Amphiphysin antibody (N-Term) (ABIN2786208)

Target: Amphiphysin (AMPH)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Amphiphysin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Amphiphysin Antibody

Binding Specificity: N-Term

Sequence: ADIKTGIFAK NVQKRLNRAQ EKVLQKLGKA DETKDEQFEE YVQNFKRQEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against AMPH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AMPH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 695 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Amphiphysin

Target: Amphiphysin (AMPH)

Alternative Name: AMPH

Background: AMPH is a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein.This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.
Alias Symbols: AMPH1
Protein Interaction Partner: PPP3CC, ARL16, CCDC67, DNM1, UBC, DNM2, AP2A1, MANEA, DYRK1A, CDK5, TERF1, Ppp3cb, REPS1, SGIP1, HCVgp1, SYNM, KHDRBS1, REPS2, SYNJ1, TP73, ITSN1, JUN, CLTC, AP2B1, ITSN2, MAPK6, TNK2, SH3GLB1, CABIN1, AP2A2, SH3GL2, CDK5R1, PLD2, BIN1, AMPH, SYN1, VTN, C
Protein Size: 695

Molecular Weight: 76 kDa

Gene ID: 273

NCBI Accession: NM_001635, NP_001626

UniProt: P49418