NCAPH2 antibody (N-Term)

Catalog No. ABIN2786231

Product Details anti-NCAPH2 Antibody

Target: NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCAPH2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EYLYSLVYQA LDFISGKRRA KQLSSVQEDR ANGVASSGVP QEAENEFLSL

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NCAPH2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NCAPH2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 605 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCAPH2

Target: NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))

Alternative Name: NCAPH2 (NCAPH2 Products)

Background: Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 and SMC4, but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II.Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM].
Alias Symbols: 384D8-2, 384D8_6, CAP-H2, MGC15858, MGC18000, MGC2455, MGC4133, MGC5305, MGC8640, hCAP-H2, CAPH2
Protein Interaction Partner: EGLN3, USHBP1, SNRPC, UBC, EGFR, LMO2, FOLR1, NCAPG2, NCAPD3, SMC2, SMC4,
Protein Size: 605

Molecular Weight: 68 kDa

Gene ID: 29781

NCBI Accession: NM_152299, NP_689512

UniProt: Q6IBW4