USP12 antibody (Middle Region)

Catalog No. ABIN2786383

This anti-USP12 antibody is a Rabbit Polyclonal antibody detecting USP12 in WB. Suitable for Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio).

Quick Overview for USP12 antibody (Middle Region) (ABIN2786383)

Target: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP12 Antibody

Binding Specificity: Middle Region

Sequence: ITRLRKENEL FDNYMQQDAH EFLNYLLNTI ADILQEERKQ EKQNGRLPNG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against USP12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 370 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP12

Target: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Alternative Name: USP12

Background: USP12 is a deubiquitinating enzyme. USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. USP12 is not involved in deubiquitination of monoubiquitinated FANCD2.
Alias Symbols: USP12L1, UBH1
Protein Interaction Partner: PHLPP1, PHLPP2, NOTCH1, AR, WDR48, UBC, APP, ITCH, WDR20, WDR26, WDR77, HIST2H2BE, HIST2H2AC, DMWD, RAD51AP1, PAIP1, MMP2, DHX8, USP46, UCHL5, SDF4, NUP160, USP39,
Protein Size: 370

Molecular Weight: 43 kDa

Gene ID: 219333

NCBI Accession: NM_182488, NP_872294

UniProt: O75317