Phospholipase C beta 1 antibody (Middle Region)

Catalog No. ABIN2786397

This anti-Phospholipase C beta 1 antibody is a Rabbit Polyclonal antibody detecting Phospholipase C beta 1 in WB. Suitable for Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit and Horse.

Quick Overview for Phospholipase C beta 1 antibody (Middle Region) (ABIN2786397)

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Phospholipase C beta 1 Antibody

Binding Specificity: Middle Region

Sequence: EAQSKRQEKL VEKHKEIRQQ ILDEKPKGEG SSSFLSETCH EDPSVSPNFT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PLCB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLCB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1173 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Alternative Name: PLCB1

Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction
Alias Symbols: FLJ45792, PI-PLC, PLC-154, PLC-I, EIEE12, PLC154, PLCB1A, PLCB1B
Protein Interaction Partner: TFCP2, CTBP2, CTBP1, CEP76, PLCB1, GNAQ, SLC9A3R1, GNA11, PCF11, UBC, KRIT1, SPTBN1, TRPC3, TRPM7, PARD6A, PARD3, RGS4, RGS12, MAPK3, PRKCD, PRKCA, MAPK1,
Protein Size: 1173

Molecular Weight: 134 kDa

Gene ID: 23236

NCBI Accession: NM_182734, NP_877398

UniProt: D3DW13

Pathways: WNT Signaling, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events