Monoamine Oxidase A antibody (N-Term)

Catalog No. ABIN2786499

The Rabbit Polyclonal anti-Monoamine Oxidase A antibody has been validated for WB. It is suitable to detect Monoamine Oxidase A in samples from Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Rabbit and Horse. There is 1 publication available.

Quick Overview for Monoamine Oxidase A antibody (N-Term) (ABIN2786499)

Target: Monoamine Oxidase A (MAOA)

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Monoamine Oxidase A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Monoamine Oxidase A Antibody

Binding Specificity: N-Term

Sequence: GPTQNRILRL SKELGIETYK VNVSERLVQY VKGKTYPFRG AFPPVWNPIA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against MAOA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAOA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 527 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Monoamine Oxidase A antibody (ABIN2786499)

Neumann, Grobe, Weisgut, Schwelberger, Fogel, Marušáková, Wache, Bähre, Buchwalow, Dhein, Hofmann, Kirchhefer, Gergs: "Histamine can be Formed and Degraded in the Human and Mouse Heart." in: Frontiers in pharmacology, Vol. 12, pp. 582916, (2021) (PubMed).

Target Details for Monoamine Oxidase A

Target: Monoamine Oxidase A (MAOA)

Alternative Name: MAOA

Background: MAOA catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAO-A
Protein Interaction Partner: NDRG1, UBC, MAOA,
Protein Size: 527

Molecular Weight: 60 kDa

Gene ID: 4128

NCBI Accession: NM_000240, NP_000231

UniProt: P21397