PPP2R2D antibody (C-Term)

Catalog No. ABIN2786544

The Rabbit Polyclonal anti-PPP2R2D antibody is suitable to detect PPP2R2D in samples from Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PPP2R2D antibody (C-Term) (ABIN2786544)

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP2R2D Antibody

Binding Specificity: C-Term

Sequence: RRDVTLEASR ENSKPRASLK PRKVCTGGKR KKDEISVDSL DFNKKILHTA

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Ppp2r2d. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 453 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R2D

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Alternative Name: Ppp2r2d

Background: Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
Alias Symbols: 1300017E19Rik, D7Ertd753e, MDS026
Protein Interaction Partner: Supt5, SMURF1, SMAD3, SMAD2,
Protein Size: 453

Molecular Weight: 50 kDa

Gene ID: 52432

NCBI Accession: NM_026391, NP_080667

UniProt: Q925E7