UNC45A antibody (Middle Region)

Catalog No. ABIN2786607

The Rabbit Polyclonal anti-UNC45A antibody has been validated for WB and IHC. It is suitable to detect UNC45A in samples from Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse and Dog.

Quick Overview for UNC45A antibody (Middle Region) (ABIN2786607)

Target: UNC45A (Unc-45 Homolog A (UNC45A))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC45A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-UNC45A Antibody

Binding Specificity: Middle Region

Sequence: REIASTLMES EMMEILSVLA KGDHSPVTRA AAACLDKAVE YGLIQPNQDG

Predicted Reactivity: Cow: 85%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UNC45A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UNC45A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 929 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UNC45A

Target: UNC45A (Unc-45 Homolog A (UNC45A))

Alternative Name: UNC45A

Background: UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR, MIM 607311) and HSP90 (HSPCA, MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway.
Alias Symbols: FLJ10043, GC-UNC45, IRO039700, SMAP-1, SMAP1, GCUNC45, GCUNC-45
Protein Interaction Partner: KRTAP10-3, MARCH10, MID2, HUWE1, MEOX2, MAX, CDC37, FAM83H, UBC, ACBD3, UGGT1, CSNK1E, CSNK1A1, gag-pol, SMAD9, HSP90AA1, ESR1, WDR5, USP14, USP1, UFD1L, UBE3A, RPA3, TWF1, PSMD13, CSE1L, TXNDC5, UCHL5, UBXN1, FBXO25, CLN3, USP19,
Protein Size: 929

Molecular Weight: 102 kDa

Gene ID: 55898

NCBI Accession: NM_001039675, NP_001034764

UniProt: A8K6F7