MTMR12 antibody (Middle Region)

Catalog No. ABIN503906

The Rabbit Polyclonal anti-MTMR12 antibody has been validated for WB. It is suitable to detect MTMR12 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Rabbit.

Quick Overview for MTMR12 antibody (Middle Region) (ABIN503906)

Target: MTMR12 (Myotubularin Related Protein 12 (MTMR12))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTMR12 Antibody

Binding Specificity: Middle Region

Sequence: RNSARLSSLF PFALLQRHSS KPVLPTSGWK ALGDEDDLAK REDEFVDLGD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MTMR12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MTMR12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 747 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTMR12

Target: MTMR12 (Myotubularin Related Protein 12 (MTMR12))

Alternative Name: MTMR12

Background: MTMR12 inactives phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Alias Symbols: 3-PAP, PIP3AP
Protein Interaction Partner: YWHAB, UBC, MTM1,
Protein Size: 747

Molecular Weight: 86 kDa

Gene ID: 54545

NCBI Accession: NM_001040446, NP_001035536

UniProt: Q9C0I1