ACO2 antibody (C-Term)

Catalog No. ABIN2786628

The Rabbit Polyclonal anti-ACO2 antibody has been validated for WB and IHC. It is suitable to detect ACO2 in samples from Human, Rat, Pig, Cow and Saccharomyces cerevisiae. There is 1 publication available.

Quick Overview for ACO2 antibody (C-Term) (ABIN2786628)

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reactivity: Human, Rat, Pig, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ACO2 Antibody

Binding Specificity: C-Term

Sequence: RYYKKHGIRW VVIGDENYGE GSSREHAALE PRHLGGRAII TKSFARIHET

Predicted Reactivity: Cow: 100%, Human: 100%, Pig: 100%, Rat: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against ACO2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ACO2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 780 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACO2 antibody (ABIN2786628)

Scheving, Wittig, Heide, Albuquerque, Steger, Brandt, Tegeder: "Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve." in: Journal of proteomics, Vol. 75, Issue 13, pp. 3987-4004, (2012) (PubMed).

Target Details for ACO2

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Alternative Name: ACO2

Background: ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
Alias Symbols: ACONM, MGC20605, MGC33908
Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, MDM2, ASB9, VCAM1, ITGA4, AK3, SIN3A, ACAA2, APP, ACAT1, ATXN1L, SUMO4, PSMD4, SRRM2,
Protein Size: 780

Molecular Weight: 82 kDa

Gene ID: 50

NCBI Accession: NM_001098, NP_001089

UniProt: Q99798