NDN antibody (Middle Region)

Catalog No. ABIN2786660

This anti-NDN antibody is a Rabbit Polyclonal antibody detecting NDN in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Goat, Horse, Pig, Rabbit, Sheep and Guinea Pig.

Quick Overview for NDN antibody (Middle Region) (ABIN2786660)

Target: NDN (Necdin Homolog (Mouse) (NDN))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Horse, Pig, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDN Antibody

Binding Specificity: Middle Region

Sequence: VALSNRMPMT GLLLMILSLI YVKGRGARES AVWNVLRILG LRPWKKHSTF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against NDN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 321 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDN

Target: NDN (Necdin Homolog (Mouse) (NDN))

Alternative Name: NDN

Background: This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress growth in postmitotic
Alias Symbols: HsT16328, PWCR
Protein Interaction Partner: IL32, FAM131C, P4HA3, N6AMT2, FSD2, SSX2IP, DTNBP1, GKAP1, CCDC136, LAX1, MIER2, APBB1IP, ZBTB7B, SERTAD3, BLOC1S6, IFFO1, EID1, MKRN2, ZBTB1, CALCOCO2, FXR2, LPXN, PPFIA1, U2AF1, TP53, NEFL, GOLGA2, CDR2, TFIP11, MPP6, UBC, EPAS1, Rtn4, EID2, EID2B, NSMC
Protein Size: 321

Molecular Weight: 36 kDa

Gene ID: 4692

NCBI Accession: NM_002487, NP_002478

UniProt: Q99608

Pathways: Neurotrophin Signaling Pathway