NPTX2 antibody (Middle Region)

Catalog No. ABIN2786663

This Rabbit Polyclonal antibody specifically detects NPTX2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for NPTX2 antibody (Middle Region) (ABIN2786663)

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPTX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPTX2 Antibody

Binding Specificity: Middle Region

Sequence: ELEDEKSLLH NETSAHRQKT ESTLNALLQR VTELERGNSA FKSPDAFKVS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against NPTX2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPTX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 431 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPTX2

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Alternative Name: NPTX2

Background: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alias Symbols: NARP, NP-II, NP2
Protein Interaction Partner: NPTXR, Nptx1,
Protein Size: 431

Molecular Weight: 47 kDa

Gene ID: 4885

NCBI Accession: NM_002523, NP_002514

UniProt: P47972