Phosphoglucomutase 1 antibody (Middle Region)
Quick Overview for Phosphoglucomutase 1 antibody (Middle Region) (ABIN2786673)
Target
See all Phosphoglucomutase 1 (PGM1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- TVEKADNFEY SDPVDGSISR NQGLRLIFTD GSRIVFRLSG TGSAGATIRL
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Predicted Reactivity
- Cow: 93%, Dog: 93%, Goat: 85%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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Characteristics
- This is a rabbit polyclonal antibody against PGM1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PGM1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 562 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Phosphoglucomutase 1 (PGM1)
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Alternative Name
- PGM1
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Background
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PGM1 is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90 % of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14.
Alias Symbols: GSD14
Protein Interaction Partner: FUS, UBC, PAXIP1, FUBP1, TALDO1, MDH1, FH, APP, GRHPR, NIT2, PGM2, USP4, TERF2IP, TINF2, POT1, TERF1, UBA5, S100B, S100A1,
Protein Size: 562 -
Molecular Weight
- 61 kDa
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Gene ID
- 5236
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NCBI Accession
- NM_002633, NP_002624
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UniProt
- P36871
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Pathways
- Cellular Glucan Metabolic Process
Target
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