Pleckstrin antibody (N-Term)

Catalog No. ABIN2786679

This Rabbit Polyclonal antibody specifically detects Pleckstrin in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog and Horse.

Quick Overview for Pleckstrin antibody (N-Term) (ABIN2786679)

Target: Pleckstrin (PLEK)

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pleckstrin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Pleckstrin Antibody

Binding Specificity: N-Term

Sequence: MEPKRIREGY LVKKGSVFNT WKPMWVVLLE DGIEFYKKKS DNSPKGMIPL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PLEK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PLEK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 350 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Pleckstrin

Target: Pleckstrin (PLEK)

Alternative Name: PLEK

Background: PLEK is a major protein kinase C substrate of platelets, its exact function is not known.
Alias Symbols: FLJ27168, P47
Protein Interaction Partner: UBC, PLEK, INPP5A, TGFBR1, ACVR1,
Protein Size: 350

Molecular Weight: 40 kDa

Gene ID: 5341

NCBI Accession: NM_002664, NP_002655

UniProt: P08567

Pathways: Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process