PKC gamma antibody (N-Term)
Quick Overview for PKC gamma antibody (N-Term) (ABIN2786695)
Target
See all PKC gamma (PRKCG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- FVVHRRCHEF VTFECPGAGK GPQTDDPRNK HKFRLHSYSS PTFCDHCGSL
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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Characteristics
- This is a rabbit polyclonal antibody against PRKCG. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 697 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
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Alternative Name
- PRKCG
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Background
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Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in d
Alias Symbols: MGC57564, PKC-gamma, PKCC, PKCG, SCA14
Protein Interaction Partner: GFAP, EPHB1, ARHGEF25, TRIM5, RANBP10, RANBP9, SCN3A, HSPA4, ITGB2, HSP90AA1, GSK3A, CASR, Marcks, SDC2, APP, TOP2A, CCHCR1, IBTK, NOXA1, EXOC5, PICK1, DDX58, PRKCG, NFE2L2, UBC, OCLN, PARD6B, PPP1R14A, GRIN1, HABP4, AFAP1, MARK4, GABRA4, CHAT, PEBP1, PAR
Protein Size: 697 -
Molecular Weight
- 78 kDa
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Gene ID
- 5582
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NCBI Accession
- NM_002739, NP_002730
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UniProt
- P05129
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Pathways
- WNT Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
Target
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