MAPK6 antibody (Middle Region)

Catalog No. ABIN2786700

This Rabbit Polyclonal antibody specifically detects MAPK6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for MAPK6 antibody (Middle Region) (ABIN2786700)

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAPK6 Antibody

Binding Specificity: Middle Region

Sequence: QVDPRKYLDG DREKYLEDPA FDTNYSTEPC WQYSDHHENK YCDLECSHTC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against MAPK6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAPK6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 721 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAPK6

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Alternative Name: MAPK6

Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
Alias Symbols: DKFZp686F03189, ERK3, HsT17250, PRKM6, p97MAPK
Protein Interaction Partner: MAPKAPK5, AURKA, HERC2, NEURL4, PSMA7, MAPK6, A2M, EIF2S3, EGLN3, vif, GALNT7, MBIP, SLC20A1, JUNB, KDSR, CCND3, ELAVL1, UBE3A, UBC, FOXO3, EMD, EIF4A1, EEF1A2, PHC2, DKC1, DDOST, DBN1, CNTN1, CFL1, CDH13, CASP6, CALR, DDR1, CA12, CA1, ATP5J, ARHGDIA, APO
Protein Size: 721

Molecular Weight: 83 kDa

Gene ID: 5597

NCBI Accession: NM_002748, NP_002739

UniProt: Q16659

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C