RANGAP1 antibody (N-Term)

Catalog No. ABIN2786743

This anti-RANGAP1 antibody is a Rabbit Polyclonal antibody detecting RANGAP1 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit. This Primary Antibody has been cited in 1 publication.

Quick Overview for RANGAP1 antibody (N-Term) (ABIN2786743)

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANGAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RANGAP1 Antibody

Binding Specificity: N-Term

Sequence: MASEDIAKLA ETLAKTQVAG GQLSFKGKSL KLNTAEDAKD VIKEIEDFDS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RANGAP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RANGAP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 587 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RANGAP1 antibody (ABIN2786743)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for RANGAP1

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Alternative Name: RANGAP1

Background: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA
Alias Symbols: Fug1, KIAA1835, MGC20266, SD
Protein Interaction Partner: SENP2, SENP1, SUMO1, UBE2I, SUMO2, SUMO3, RANBP2, UBC, NEDD8, RNF2, rev, TP53RK, EFTUD1, NIF3L1, RPRD1B, OSGEP, PANK4, THG1L, NSUN2, UFM1, IPO11, SH3GLB1, TPRKB, EEF2K, DBNL, KIAA1279, ACTR2, ACTR3, ARPC1B, SAE1, TPD52L2, PPP2R5D, LPP, CALU, BAG1, ARPC2,
Protein Size: 587

Molecular Weight: 63 kDa

Gene ID: 5905

NCBI Accession: NM_002883, NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus