MOS antibody (Middle Region)
Quick Overview for MOS antibody (Middle Region) (ABIN2786805)
Target
See all MOS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- LNVARLRHDN IVRVVAASTR TPAGSNSLGT IIMEFGGNVT LHQVIYGAAG
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Predicted Reactivity
- Cow: 92%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against MOS. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MOS
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 346 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MOS (Moloney Sarcoma Oncogene (MOS))
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Alternative Name
- MOS
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Background
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MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1, MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).
Alias Symbols: MGC119962, MGC119963, MSV
Protein Interaction Partner: CALCOCO2, SEC24C, HOMER3, TRAF1, TRIM27, KRT15, KRT13, KIFC3, GOLGA2, GFAP, ACTN2, LZTS2, USHBP1, CCDC33, CCDC102B, MTMR9, CCDC136, C17orf59, CCNDBP1, MID2, ATRIP, SPERT, DYDC1, KRT40, SSX2IP, HECW2, HSP90AA1, BMPR2, MYOD1, HSPA1A,
Protein Size: 346 -
Molecular Weight
- 38 kDa
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Gene ID
- 4342
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NCBI Accession
- NM_005372, NP_005363
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UniProt
- P00540
Target
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