PRKAB2 antibody (Middle Region)

Catalog No. ABIN2786810

There is 1 publication for this product available. The Rabbit Polyclonal anti-PRKAB2 antibody is suitable to detect PRKAB2 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PRKAB2 antibody (Middle Region) (ABIN2786810)

Target: PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKAB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRKAB2 Antibody

Binding Specificity: Middle Region

Sequence: RDLSSSPPGP YGQEMYAFRS EERFKSPPIL PPHLLQVILN KDTNISCDPA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PRKAB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRKAB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 272 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PRKAB2 antibody (ABIN2786810)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for PRKAB2

Target: PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))

Alternative Name: PRKAB2

Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme tha
Alias Symbols: MGC61468
Protein Interaction Partner: MAGED1, PIAS2, STX11, BLZF1, TRAF2, STX19, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-9, KRTAP10-7, CCDC36, KRT40, RHEBL1, UBXN11, CREB3L1, RIMBP3, KRTAP4-2, KRTAP9-4, LZTS2, KRTAP9-2, KRTAP4-12, CCDC33, BEND5, GATAD2B, BANP, FAM208B, GET4, KLF15, IKZF3, IK
Protein Size: 272

Molecular Weight: 30 kDa

Gene ID: 5565

NCBI Accession: NM_005399, NP_005390

UniProt: O43741

Pathways: AMPK Signaling, Warburg Effect