Relaxin 1 antibody (Middle Region)

Catalog No. ABIN2786863

The Rabbit Polyclonal anti-Relaxin 1 antibody has been validated for WB. It is suitable to detect Relaxin 1 in samples from Human, Rat and Pig.

Quick Overview for Relaxin 1 antibody (Middle Region) (ABIN2786863)

Target: Relaxin 1 (RLN1)

Reactivity: Human, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Relaxin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Relaxin 1 Antibody

Binding Specificity: Middle Region

Sequence: EIVPSFINKD TETIIIMLEF IANLPPELKA ALSERQPSLP ELQQYVPALK

Predicted Reactivity: Human: 100%, Pig: 92%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against RLN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RLN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 185 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Relaxin 1

Target: Relaxin 1 (RLN1)

Alternative Name: RLN1

Background: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds, however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.
Alias Symbols: H1, RLXH1, bA12D24.3.1, bA12D24.3.2
Protein Interaction Partner: RXFP1,
Protein Size: 185

Molecular Weight: 21 kDa

Gene ID: 6013

NCBI Accession: NM_006911, NP_008842

UniProt: P04808