APIP antibody (Middle Region)

Catalog No. ABIN2786905

This Rabbit Polyclonal antibody specifically detects APIP in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for APIP antibody (Middle Region) (ABIN2786905)

Target: APIP (APAF1 Interacting Protein (APIP))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APIP Antibody

Binding Specificity: Middle Region

Sequence: GIKKCTSGGY YRYDDMLVVP IIENTPEEKD LKDRMAHAMN EYPDSCAVLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against APIP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APIP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 242 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for APIP

Target: APIP (APAF1 Interacting Protein (APIP))

Alternative Name: APIP

Background: APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).
Alias Symbols: APIP2, CGI-29, MMRP19, dJ179L10.2, CGI29
Protein Interaction Partner: C6orf165, LNX1, TSC22D4, PDZD4, WDYHV1, APIP, TNPO2, ZBTB25, SKP1, SDCBP, PSMA1, IMPDH2, SUMO1, UBC, NEDD8, NUDT18, NIF3L1, PPP1CC, ELAVL1, VPS25, APAF1, VIM,
Protein Size: 242

Molecular Weight: 27 kDa

Gene ID: 51074

NCBI Accession: NM_015957, NP_057041

UniProt: Q96GX9

Pathways: Methionine Biosynthetic Process