PPME1 antibody (N-Term)

Catalog No. ABIN2786934

The Rabbit Polyclonal anti-PPME1 antibody (ABIN2786934) specifically detects PPME1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse and Rabbit samples.

Quick Overview for PPME1 antibody (N-Term) (ABIN2786934)

Target: PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPME1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PPME1 Antibody

Binding Specificity: N-Term

Sequence: PGRKRDFSPV PWSQYFESME DVEVENETGK DTFRVYKSGS EGPVLLLLHG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 81%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PPME1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPME1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 386 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPME1

Target: PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))

Alternative Name: PPME1

Background: Protein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit.Protein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit (PPP2CA, MIM 176915) (Ogris et al., 1999 [PubMed 10318862]).[supplied by OMIM].
Alias Symbols: FLJ22226, PME-1
Protein Interaction Partner: TOM1L1, ZPR1, GMPS, OGT, TSTA3, SURF2, PSMD5, PPP1R7, PNP, LPP, AGFG1, HNRNPF, ALAD, LRSAM1, C14orf142, COASY, P3H1, FKBP10, RPRD1B, ERO1L, DBNL, HSPBP1, TTLL12, GPN1, WDR4, ACTR2, UBC, TJAP1, NUDC, SLC9A3R1, RPA1, Ppp2r1a, TDRD1, PPP2R2D, PPP4C, PPP2CB,
Protein Size: 386

Molecular Weight: 42 kDa

Gene ID: 51400

NCBI Accession: NM_016147, NP_057231

UniProt: Q9Y570

Pathways: Methionine Biosynthetic Process