DCDC2 antibody (Middle Region)

Catalog No. ABIN2786961

This Rabbit Polyclonal antibody specifically detects DCDC2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow and Horse.

Quick Overview for DCDC2 antibody (Middle Region) (ABIN2786961)

Target: DCDC2 (Doublecortin Domain Containing 2 (DCDC2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCDC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DCDC2 Antibody

Binding Specificity: Middle Region

Sequence: KGSGNDRHSK STVGSSDNSS PQPLKRKGKK EDVNSEKLTK LKQNVKLKNS

Predicted Reactivity: Cow: 93%, Dog: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DCDC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DCDC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DCDC2

Target: DCDC2 (Doublecortin Domain Containing 2 (DCDC2))

Alternative Name: DCDC2

Background: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Mutations in this gene have been associated with Reading Disability (RD), also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: DCDC2A, RU2, RU2S
Protein Interaction Partner: MRFAP1, NIF3L1, APP,
Protein Size: 476

Molecular Weight: 53 kDa

Gene ID: 51473

NCBI Accession: NM_016356, NP_057440

UniProt: Q9UHG0