ERCC6L antibody (N-Term)
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- Target See all ERCC6L Antibodies
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
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Binding Specificity
- N-Term
- Reactivity
- Human, Rat, Horse, Cow, Dog, Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERCC6L antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GDLEEAFKLF NLAKDIFPNE KVLSRIQKIQ EALEELAEQG DDEFTDVCNS
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against ERCC6L. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC6L
- Top Product
- Discover our top product ERCC6L Primary Antibody
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anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) (AA 1-419) antibody
ERCC6L Reactivity: Human ELISA, WB Host: Mouse Monoclonal 3F12-2B10 unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) (AA 1-419) antibodyERCC6L Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) (AA 1-419) antibodyERCC6L Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) (AA 1-419) antibodyERCC6L Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) (AA 35-84) antibodyERCC6L Reactivity: Human, Rat, Horse, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) (AA 300-400) antibodyERCC6L Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) (N-Term) antibodyERCC6L Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1250 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
- Alternative Name
- ERCC6L (ERCC6L Products)
- Background
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ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint.ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
Alias Symbols: FLJ20105, MGC131695, PICH
Protein Interaction Partner: LMO4, UBC, HTT, BARD1, ACACA, Ercc6l, Plk1, RB1CC1, RPA3,
Protein Size: 1250 - Molecular Weight
- 141 kDa
- Gene ID
- 54821
- NCBI Accession
- NM_017669, NP_060139
- UniProt
- Q2NKX8
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