ERCC6L antibody (AA 1-419)

Catalog No. ABIN565778

The Mouse Monoclonal anti-ERCC6L antibody has been validated for ELISA and WB. It is suitable to detect ERCC6L in samples from Human. There are 3+ publications available.

Quick Overview for ERCC6L antibody (AA 1-419) (ABIN565778)

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERCC6L antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 3F12-2B10

Product Details anti-ERCC6L Antibody

Binding Specificity: AA 1-419

Purpose: Mouse monoclonal antibody raised against a full length recombinant ERCC6L.

Sequence: MEKSFATKNE AVQKETLQEG PKQEALQEDP LESFNYVLSK STKADIGPNL DQLKDDEILR HCNPWPIISI TNESQNAESN VSIIEIADDL SASHSALQDA QASEAKLEEE PSASSPQYAC DFNLFLEDSA DNRQNFSSQS LEHVEKENSL CGSAPNSRAG FVHSKTCLSW EFSEKDDEPE EVVVKAKIRS KARRIVSDGE DEDDSFKDTS SINPFNTSLF QFSSVKQFDA STPKNDISPP GRFFSSQIPS SVNKSMNSRR SLASRRSLIN MVLDHVEDME ERLDDSSEAK GPEDYPEEGV EESSGEASKY TEEDPSGETL SSENKSSWLM TSKPSALAQE TSLGAPEPLS GEQLVGSPQD KAAEATNDYE TLVKRGKELK ECGKIQEALN CLVKALDIKS ADPEVMLLTL SLYKQLNNN

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ERCC6L (AAH08808, 1 a.a. ~ 419 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ERCC6L antibody (ABIN565778)

Gemble, Buhagiar-Labarchède, Onclercq-Delic, Biard, Lambert, Amor-Guéret: "A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation." in: Journal of cell science, Vol. 129, Issue 16, pp. 3167-77, (2016) (PubMed).

Kurasawa, Yu-Lee: "PICH and cotargeted Plk1 coordinately maintain prometaphase chromosome arm architecture." in: Molecular biology of the cell, Vol. 21, Issue 7, pp. 1188-99, (2010) (PubMed).

Leng, Bessuso, Jung, Wang, Qin: "Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 10, pp. 1480-9, (2008) (PubMed).

Target Details for ERCC6L

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Alternative Name: ERCC6L

Background: Full Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 6-like
Synonyms: FLJ20105,MGC131695,PICH

Gene ID: 54821