ERCC6L antibody (AA 1-419)

Catalog No. ABIN527207

There are 6+ publications for this product available. The Rabbit Polyclonal anti-ERCC6L antibody is suitable to detect ERCC6L in samples from Human. It has been validated for WB.

Quick Overview for ERCC6L antibody (AA 1-419) (ABIN527207)

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC6L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERCC6L Antibody

Binding Specificity: AA 1-419

Purpose: Rabbit polyclonal antibody raised against a full-length human ERCC6L protein.

Sequence: MEKSFATKNE AVQKETLQEG PKQEALQEDP LESFNYVLSK STKADIGPNL DQLKDDEILR HCNPWPIISI TNESQNAESN VSIIEIADDL SASHSALQDA QASEAKLEEE PSASSPQYAC DFNLFLEDSA DNRQNFSSQS LEHVEKENSL CGSAPNSRAG FVHSKTCLSW EFSEKDDEPE EVVVKAKIRS KARRIVSDGE DEDDSFKDTS SINPFNTSLF QFSSVKQFDA STPKNDISPP GRFFSSQIPS SVNKSMNSRR SLASRRSLIN MVLDHVEDME ERLDDSSEAK GPEDYPEEGV EESSGEASKY TEEDPSGETL SSENKSSWLM TSKPSALAQE TSLGAPEPLS GEQLVGSPQD KAAEATNDYE TLVKRGKELK ECGKIQEALN CLVKALDIKS ADPEVMLLTL SLYKQLNNN

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: ERCC6L (AAH08808.1, 1 a.a. ~ 419 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1mg/ml

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ERCC6L antibody (ABIN527207)

Gemble, Buhagiar-Labarchède, Onclercq-Delic, Biard, Lambert, Amor-Guéret: "A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation." in: Journal of cell science, Vol. 129, Issue 16, pp. 3167-77, (2016) (PubMed).

Kang, Song, Du, Zhang, Liu, Liang, He, Lamb, Shen, Yin: "PTEN stabilizes TOP2A and regulates the DNA decatenation." in: Scientific reports, Vol. 5, pp. 17873, (2015) (PubMed).

Luebben, Kawabata, Johnson, OSullivan, Shima: "A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5605-15, (2014) (PubMed).

Rouzeau, Cordelières, Buhagiar-Labarchède, Hurbain, Onclercq-Delic, Gemble, Magnaghi-Jaulin, Jaulin, Amor-Guéret: "Bloom's syndrome and PICH helicases cooperate with topoisomerase II? in centromere disjunction before anaphase." in: PLoS ONE, Vol. 7, Issue 4, pp. e33905, (2012) (PubMed).

Muñoz, Laulier, Gunn, Cheng, Robbiani, Nussenzweig, Stark: "RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1." in: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40618-28, (2012) (PubMed).

Laulier, Cheng, Stark: "The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation." in: Nucleic acids research, Vol. 39, Issue 14, pp. 5935-44, (2011) (PubMed).

Target Details for ERCC6L

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Alternative Name: ERCC6L

Background: Full Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 6-like
Synonyms: FLJ20105,MGC131695,PICH

Gene ID: 54821