FBXO34 antibody (Middle Region)

Catalog No. ABIN2787049

The Rabbit Polyclonal anti-FBXO34 antibody is suitable to detect FBXO34 in samples from Human, Rat, Guinea Pig, Mouse, Cow, Rabbit, Dog and Horse. It has been validated for WB.

Quick Overview for FBXO34 antibody (Middle Region) (ABIN2787049)

Target: FBXO34 (F-Box Protein 34 (FBXO34))

Reactivity: Human, Rat, Guinea Pig, Mouse, Cow, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO34 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO34 Antibody

Binding Specificity: Middle Region

Sequence: ESECLKRQGQ REPGSLSRNN SFRRNVGRVL LANSTQADEG KTKKGVLEAP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO34. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO34

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 711 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO34

Target: FBXO34 (F-Box Protein 34 (FBXO34))

Alternative Name: FBXO34

Background: Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Alias Symbols: CGI-301, DKFZp547C162, FLJ20725, Fbx34, MGC126434, MGC126435
Protein Interaction Partner: KRT40, MTUS2, MDFI, CUL1, UBC, HSP90AA1, TGFBR2, TGFBR1, SKP1, SMAD4,
Protein Size: 711

Molecular Weight: 79 kDa

Gene ID: 55030

NCBI Accession: NM_017943, NP_060413

UniProt: Q9NWN3