VPS35 antibody (C-Term)

Catalog No. ABIN2787083

This Rabbit Polyclonal antibody specifically detects VPS35 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for VPS35 antibody (C-Term) (ABIN2787083)

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS35 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VPS35 Antibody

Binding Specificity: C-Term

Sequence: VLNQLIQKIR EDLPNLESSE ETEQINKHFH NTLEHLRSRR ESPESEGPIY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Vps35. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Vps35

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 796 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VPS35

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Alternative Name: Vps35

Background: Vps35 is an essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. It is also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
Alias Symbols: AI647796, Mem3
Protein Interaction Partner: Eed, Plcb1, Vps26b, Snx1, Vps29, Vps26a,
Protein Size: 796

Molecular Weight: 88 kDa

Gene ID: 65114

NCBI Accession: NM_022997, NP_075373

UniProt: Q9EQH3