ASXL2 antibody (Middle Region)

Catalog No. ABIN2787104

The Rabbit Polyclonal anti-ASXL2 antibody (ABIN2787104) specifically detects ASXL2 in WB. The antibody is reactive with Human, Dog, Mouse, Pig, Rabbit, Rat, Cow, Guinea Pig and Horse samples.

Quick Overview for ASXL2 antibody (Middle Region) (ABIN2787104)

Target: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Reactivity: Human, Dog, Mouse, Pig, Rabbit, Rat, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASXL2 Antibody

Binding Specificity: Middle Region

Sequence: EEAPVSWEKR PRVTENRQHQ QPFQVSPQPF LNRGDRIQVR KVPPLKIPVS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ASXL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASXL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1435 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASXL2

Target: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Alternative Name: ASXL2

Background: ASXL2 is a human homolog of the Drosophila asx gene. Drosophila asx is an enhancer of trithorax (see MIM 159555) and polycomb (see MIM 610231) (ETP) gene that encodes a chromatin protein with dual functions in transcriptional activation and silencing (Katoh and Katoh, 2003 [PubMed 12888926]).
Alias Symbols: ASXH2, DKFZp686C1968, FLJ10898, KIAA1685
Protein Interaction Partner: UBC, HECW2, PRPF40A, APP, BAP1, TRAF6,
Protein Size: 1435

Molecular Weight: 154 kDa

Gene ID: 55252

NCBI Accession: NM_018263, NP_060733

UniProt: Q76L83

Pathways: Positive Regulation of fat Cell Differentiation