Pellino 1 antibody (N-Term)

Catalog No. ABIN2787222

This anti-Pellino 1 antibody is a Rabbit Polyclonal antibody detecting Pellino 1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Pellino 1 antibody (N-Term) (ABIN2787222)

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Pellino 1 Antibody

Binding Specificity: N-Term

Sequence: ESPIDFVVTD TVPGSQSNSD TQSVQSTISR FACRIICERN PPFTARIYAA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PELI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PELI1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Pellino 1

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Alternative Name: PELI1

Background: PELI1 is an scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. PELI1 is required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.
Alias Symbols: DKFZp686C18116, MGC50990
Protein Interaction Partner: UBC, VAC14, TRIP13, BCL6, SRPK2, SRPK1, DEAF1, IRAK1, UBE2V1, UBE2N, UBE2D2, UBE2D1, IRAK4, TRAF6, NR2C2, MYD88, SMAD6, IL1R1, TBK1, IKBKB, UBE2I, RIPK1, IRAK2,
Protein Size: 418

Molecular Weight: 46 kDa

Gene ID: 57162

NCBI Accession: NM_020651, NP_065702

UniProt: Q8C669

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades