TBC1D24 antibody (Middle Region)

Catalog No. ABIN2787224

The Rabbit Polyclonal anti-TBC1D24 antibody has been validated for WB. It is suitable to detect TBC1D24 in samples from Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog and Rabbit. There is 1 publication available.

Quick Overview for TBC1D24 antibody (Middle Region) (ABIN2787224)

Target: TBC1D24 (TBC1 Domain Family, Member 24 (TBC1D24))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBC1D24 Antibody

Binding Specificity: Middle Region

Sequence: SDPADRLSPF LAARHFNLPS KTESMFMAGG SDCLIVGGGG GQALYIDGDL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TBC1D24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBC1D24

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 553 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TBC1D24 antibody (ABIN2787224)

Lozano, Herman, Rothfuss, Rieger, Bayrak-Toydemir, Aprile, Fruscione, Zara, Fassio: "Clinical intrafamilial variability in lethal familial neonatal seizure disorder caused by TBC1D24 mutations." in: American journal of medical genetics. Part A, Vol. 170, Issue 12, pp. 3207-3214, (2016) (PubMed).

Target Details for TBC1D24

Target: TBC1D24 (TBC1 Domain Family, Member 24 (TBC1D24))

Alternative Name: TBC1D24

Background: TBC1D24 may act as a GTPase-activating protein for Rab family protein(s).
Alias Symbols: KIAA1171, MGC102885, FIME
Protein Interaction Partner: UBC,
Protein Size: 553

Molecular Weight: 62 kDa

Gene ID: 57465

NCBI Accession: NM_020705, NP_065756

UniProt: Q9ULP9