WFDC1 antibody (Middle Region)

Catalog No. ABIN2787263

The Rabbit Polyclonal anti-WFDC1 antibody has been validated for WB. It is suitable to detect WFDC1 in samples from Human, Rat, Dog and Pig.

Quick Overview for WFDC1 antibody (Middle Region) (ABIN2787263)

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Reactivity: Human, Rat, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WFDC1 Antibody

Binding Specificity: Middle Region

Sequence: VAEGIPNRGQ CVKQRRQADG RILRHKLYKE YPEGDSKNVA EPGRGQQKHF

Predicted Reactivity: Dog: 86%, Human: 100%, Pig: 85%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against WFDC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WFDC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 220 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WFDC1

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Alternative Name: WFDC1

Background: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.
Alias Symbols: PS20
Protein Interaction Partner: EZR, ZNF677, RAB40B, FOSL1, XRCC2,
Protein Size: 220

Molecular Weight: 21 kDa

Gene ID: 58189

NCBI Accession: NM_021197, NP_067020

UniProt: Q9HC57