MTMR14 antibody (Middle Region)
Quick Overview for MTMR14 antibody (Middle Region) (ABIN2787315)
Target
See all MTMR14 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- NFLKHITSEE FSALKTQRRK SLPARDGGFT LEDICMLRRK DRGSTTSLGS
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against MTMR14. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MTMR14
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 650 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MTMR14 (Myotubularin Related Protein 14 (MTMR14))
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Alternative Name
- MTMR14
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Background
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This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
Alias Symbols: C3orf29, FLJ22405, FLJ90311, hEDTP
Protein Interaction Partner: TP53BP2, APP, UBC,
Protein Size: 650 -
Molecular Weight
- 72 kDa
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Gene ID
- 64419
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NCBI Accession
- NM_001077525, NP_001070993
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UniProt
- Q8NCE2
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Pathways
- Inositol Metabolic Process
Target
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