MTMR14 antibody (Middle Region)

Catalog No. ABIN2787315

The Rabbit Polyclonal anti-MTMR14 antibody is suitable to detect MTMR14 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for MTMR14 antibody (Middle Region) (ABIN2787315)

Target: MTMR14 (Myotubularin Related Protein 14 (MTMR14))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTMR14 Antibody

Binding Specificity: Middle Region

Sequence: NFLKHITSEE FSALKTQRRK SLPARDGGFT LEDICMLRRK DRGSTTSLGS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MTMR14. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MTMR14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 650 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTMR14

Target: MTMR14 (Myotubularin Related Protein 14 (MTMR14))

Alternative Name: MTMR14

Background: This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.

Alias Symbols: C3orf29, FLJ22405, FLJ90311, hEDTP
Protein Interaction Partner: TP53BP2, APP, UBC,
Protein Size: 650

Molecular Weight: 72 kDa

Gene ID: 64419

NCBI Accession: NM_001077525, NP_001070993

UniProt: Q8NCE2

Pathways: Inositol Metabolic Process