AXUD1 antibody (Middle Region)
Quick Overview for AXUD1 antibody (Middle Region) (ABIN2787343)
Target
See all AXUD1 (CSRNP1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- Middle Region
-
Sequence
- ARVQTHFIHT LTRLQLEQEA ESFRELEAPA QGSPPSPGEE ALVPTFPLAK
-
Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
Characteristics
- This is a rabbit polyclonal antibody against AXUD1. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AXUD1
-
-
-
-
Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
-
Comment
-
Antigen size: 589 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))
-
Alternative Name
- AXUD1
-
Background
-
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function.
Alias Symbols: DKFZp566F164, FAM130B, TAIP-3, URAX1, AXUD1, CSRNP-1
Protein Interaction Partner: TCEANC, ZNF417, ZNF587, PPP1CC, PPP1CA, AQP1, ELAVL1,
Protein Size: 589 -
Molecular Weight
- 63 kDa
-
Gene ID
- 64651
-
NCBI Accession
- NM_033027, NP_149016
-
UniProt
- D6RBU1
-
Pathways
- Platelet-derived growth Factor Receptor Signaling
Target
-