ASB3 antibody (Middle Region)

Catalog No. ABIN2787365

This Rabbit Polyclonal antibody specifically detects ASB3 in WB. It exhibits reactivity toward Human, Cow, Dog, Guinea Pig, Horse and Rat.

Quick Overview for ASB3 antibody (Middle Region) (ABIN2787365)

Target: ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB3 Antibody

Binding Specificity: Middle Region

Sequence: LEIRSSLKSE RLRSDSYISQ LPLPRSLHNY LLYEDVLRMY EVPELAAIQD

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ASB3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 445 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB3

Target: ASB3 (Ankyrin Repeat and SOCS Box-Containing 3 (ASB3))

Alternative Name: ASB3

Background: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.
Alias Symbols: ASB-3, FLJ10123, FLJ10421, MGC12531, MGC132002, MGC996
Protein Interaction Partner: PGAM5, ASB6, DNPEP, EPB41L3, CLASP2, SLC4A1AP, THRAP3, BCLAF1, PRDX6, CUL5, TCEB2, TCEB1, SRP14, SFPQ, RPS27, RPL38, RCN2, NONO, ERH, ATP5F1, ATP5C1, SLC25A5, AGL, PRMT6, KDM1A, ZAP70, HSP90AA1, DCUN1D1, ELAVL1, TNFRSF1B, S100A9, S100A8,
Protein Size: 445

Molecular Weight: 49 kDa

Gene ID: 51130

NCBI Accession: NM_145863, NP_665862

UniProt: D6W5B5