EXOC1 antibody (N-Term)

Catalog No. ABIN2787382

The Rabbit Polyclonal anti-EXOC1 antibody has been validated for WB. It is suitable to detect EXOC1 in samples from Human, Rat, Mouse, Horse, Rabbit, Cow, Dog, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for EXOC1 antibody (N-Term) (ABIN2787382)

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EXOC1 Antibody

Binding Specificity: N-Term

Sequence: NCFLCATVTT ERPVQVKVVK VKKSDKGDFY KRQIAWALRD LAVVDAKDAI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against EXOC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 894 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOC1

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Alternative Name: EXOC1

Background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: BM-102, FLJ10893, SEC3, SEC3L1, SEC3P
Protein Interaction Partner: ATG14, RB1CC1, KIAA0226, EXOC4, IQCB1, UBD, UBC, KANSL1, SFR1, TRIM9, CEP295, NUF2, COLEC12, CCDC88A, SYBU, KIAA1551, CCDC93, CCSER2, LUC7L2, DISC1, TRAF3IP1, MACF1, SRGAP2, KDM1A, SH3BP5, TRIO, SPTAN1, KIF5A, GOLGA4, CDC5L, DST, RALA,
Protein Size: 894

Molecular Weight: 98 kDa

Gene ID: 55763

NCBI Accession: NM_018261, NP_060731

UniProt: Q9NV70

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis