RAC1 antibody (Middle Region)

Catalog No. ABIN2787398

The Rabbit Polyclonal anti-RAC1 antibody has been validated for WB. It is suitable to detect RAC1 in samples from Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Sheep, Rabbit, Horse, Cow and Guinea Pig.

Quick Overview for RAC1 antibody (Middle Region) (ABIN2787398)

Target: RAC1

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Sheep, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAC1 Antibody

Binding Specificity: Middle Region

Sequence: LAMAKEIGAV KYLECSALTQ RGLKTVFDEA IRAVLCPPPV KKRKRKCLLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RAC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 192 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAC1

Target: RAC1

Background: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC111543, MIG5, TC-25, p21-Rac1, Rac-1
Protein Interaction Partner: PAK3, NCF2, KRT40, LZTS2, PAK6, C1QA, RHOB, XIAP, BIRC2, UBC, CDC23, USH1C, TRIO, srgp-1, EED, PRMT6, HACE1, NOXA1, ARFIP2, ITGA4, GRN, FN1, BRINP1, DIAPH3, BAIAP2, LTBP4, VWF, VCAM1, MTNR1A, COX3, LTBP3, CHN2, IGBP1, CLNS1A, PSAT1, Htt, PAK1, LRRK2, SH3R
Protein Size: 192

Molecular Weight: 21 kDa

Gene ID: 5879

NCBI Accession: NM_006908, NP_008839

UniProt: P60763

Pathways: WNT Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling