GABPB2 antibody (N-Term)

Catalog No. ABIN2787434

This Rabbit Polyclonal antibody specifically detects GABPB2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Cow.

Quick Overview for GABPB2 antibody (N-Term) (ABIN2787434)

Target: GABPB2 (GA-Binding Protein Subunit beta-2 (GABPB2))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABPB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABPB2 Antibody

Binding Specificity: N-Term

Sequence: MSLVDLGKKL LEAARAGQDD EVRILMANGA PFTTDWLGTS PLHLAAQYGH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GABPB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABPB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 360 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABPB2

Target: GABPB2 (GA-Binding Protein Subunit beta-2 (GABPB2))

Alternative Name: GABPB2

Background: GABPB2 is the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB1, NRF2B1, NRF2B2, GABPB2
Protein Interaction Partner: FAM90A1, RBM11, RSPH14, TDRD7, POGZ, LMO4, TRAF2, SNRPB2, SNRPA, LMO1, UBC, MAGEB18, RYBP, YAF2, YY1, GABPA, IL16, DHX16, CIC, LMO3, USO1, FANCG, BAI2, HCFC1, ATF1,
Protein Size: 360

Molecular Weight: 38 kDa

Gene ID: 2553

NCBI Accession: NM_002041, NP_002032

UniProt: Q06547