HOXB5 antibody (N-Term)

Catalog No. ABIN2787516

This anti-HOXB5 antibody is a Rabbit Polyclonal antibody detecting HOXB5 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig and Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for HOXB5 antibody (N-Term) (ABIN2787516)

Target: HOXB5 (Homeobox B5 (HOXB5))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXB5 Antibody

Binding Specificity: N-Term

Sequence: DPAAMHTGSY GYNYNGMDLS VNRSSASSSH FGAVGESSRA FPAPAQEPRF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXB5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 269 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HOXB5 antibody (ABIN2787516)

Wu, Lothe, Ahlquist, Silins, Tropé, Micci, Nesland, Suo, Lind: "DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets." in: Molecular cancer, Vol. 6, pp. 45, (2007) (PubMed).

Target Details for HOXB5

Target: HOXB5 (Homeobox B5 (HOXB5))

Alternative Name: HOXB5

Background: HOXB5 belongs to ANTP homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. HOXB5 gene is included in a cluster of homeobox B genes located on chromosome 17.The protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
Protein Interaction Partner: MAGEA11, CTBP2, CTBP1, TRIM23, UBC,
Protein Size: 269

Molecular Weight: 29 kDa

Gene ID: 3215

NCBI Accession: NM_002147, NP_002138

UniProt: P09067