Vitronectin antibody (N-Term)

Catalog No. ABIN2787545

This Rabbit Polyclonal antibody specifically detects Vitronectin in WB. It exhibits reactivity toward Human.

Quick Overview for Vitronectin antibody (N-Term) (ABIN2787545)

Target: Vitronectin (VTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Vitronectin Antibody

Binding Specificity: N-Term

Sequence: EDEYTVYDDG EEKNNATVHE QVGGPSLTSD LQAQSKGNPE QTPVLKPEEE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against VTN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VTN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 478 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: VTN

Background: VTN is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: V75, VN, VNT
Protein Interaction Partner: GOPC, EED, ADH5, RHOXF1, ADTRP, ETV7, RPL13A, CBX1, PRDX4, CRADD, SIX1, GLUD1, CKS2, CD247, PRKCA, PRKACA, RBM25, WDR18, PRPF40A, SMU1, LUC7L3, SF3B6, HP1BP3, PRPF19, PHGDH, SF3B1, SF3B3, SRSF10, USP39, PRPF8, SF3A1, SAP18, HNRNPR, RBM39, SRSF11, BUD31, D
Protein Size: 478

Molecular Weight: 52 kDa

Gene ID: 7448

NCBI Accession: NM_000638, NP_000629

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration