Vitronectin antibody

Catalog No. ABIN2855638

Product Details anti-Vitronectin Antibody

Target: Vitronectin (VTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to Vitronectin (vitronectin)
Vitronectin antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Vitronectin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse brain

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.34 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: vitronectin (VTN Products)

Synonyms: VTN antibody, DKFZp470F0511 antibody, LOC100228142 antibody, vtn antibody, zgc:112277 antibody, V75 antibody, VN antibody, VNT antibody, AI256434 antibody, Vn antibody, Aa1018 antibody, vitronectin antibody, vitronectin a antibody, vitronectin b antibody, vitronectin L homeolog antibody, VTN antibody, vtn antibody, vtna antibody, vtnb antibody, CpipJ_CPIJ016691 antibody, vtn.L antibody, Vtn antibody

Background: The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Cellular Localization: Secreted , extracellular space

Molecular Weight: 54 kDa

Gene ID: 7448

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration