TFEB antibody (Middle Region)

Catalog No. ABIN2787554

The Rabbit Polyclonal anti-TFEB antibody has been validated for WB. It is suitable to detect TFEB in samples from Human, Cow, Dog, Horse, Goat and Rabbit.

Quick Overview for TFEB antibody (Middle Region) (ABIN2787554)

Target: TFEB (Transcription Factor EB (TFEB))

Reactivity: Human, Cow, Dog, Horse, Goat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFEB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TFEB Antibody

Binding Specificity: Middle Region

Sequence: DFSHSLSFGG REDEGPPGYP EPLAPGHGSP FPSLSKKDLD LMLLDDSLLP

Predicted Reactivity: Cow: 79%, Dog: 86%, Goat: 79%, Horse: 85%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against TFEB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TFEB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFEB

Target: TFEB (Transcription Factor EB (TFEB))

Alternative Name: TFEB

Background: The TFEB gene fuses with an intronless gene in renal tumors harboring the t(6,11)(p21,q13) chromosome translocation. It encodes a protein that is a highly sensitive and specific diagnostic marker for renal neoplasms.
Alias Symbols: AlphaTFEB, TCFEB, BHLHE35, ALPHATFEB
Protein Interaction Partner: SRPK1, YWHAQ, TFEC, TFE3, MITF,
Protein Size: 476

Molecular Weight: 53 kDa

Gene ID: 7942

NCBI Accession: NM_007162, NP_009093

UniProt: P19484