BPGM antibody (Middle Region)

Catalog No. ABIN2787596

The Rabbit Polyclonal anti-BPGM antibody (ABIN2787596) specifically detects BPGM in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio) samples.

Quick Overview for BPGM antibody (Middle Region) (ABIN2787596)

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPGM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BPGM Antibody

Binding Specificity: Middle Region

Sequence: EQVRLWRRSY NVTPPPIEES HPYYQEIYND RRYKVCDVPL DQLPRSESLK

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against BPGM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BPGM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 259 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BPGM

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Alternative Name: BPGM

Background: BPGM belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily. It plays a major role in regulating hemoglobin oxygen affinity as a consequence of controlling 2,3-BPG concentration. It can also catalyze the reaction of EC 5.4.2.1 (mutase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
Alias Symbols: DPGM
Protein Interaction Partner: UBC, EHD2, ATF6, NEK3, EGR2, CEL, ATP4B, SPEN, GRB2, AKT1, GAPDH,
Protein Size: 259

Molecular Weight: 28 kDa

Gene ID: 669

NCBI Accession: NM_001724, NP_001715

UniProt: P07738