DUSP5 antibody (Middle Region)

Catalog No. ABIN2787599

This anti-DUSP5 antibody is a Rabbit Polyclonal antibody detecting DUSP5 in WB. Suitable for Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig and Pig.

Quick Overview for DUSP5 antibody (Middle Region) (ABIN2787599)

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DUSP5 Antibody

Binding Specificity: Middle Region

Sequence: AGSSLIGHLQ TLSPDMQGAY CTFPASVLAP VPTHSTVSEL SRSPVATATS

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against DUSP5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DUSP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DUSP5

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Alternative Name: DUSP5

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Alias Symbols: DUSP, HVH3
Protein Interaction Partner: ELAVL1, UBC, MAPK3, MAPK1,
Protein Size: 384

Molecular Weight: 42 kDa

Gene ID: 1847

NCBI Accession: NM_004419, NP_004410

UniProt: Q16690